Janus Henderson Global Life Sciences Fund Class I (JFNIX) Fund Details & Analysis

Fund Information

Fund Category Health

Fund Family Janus Henderson

Fund Style Large Blend

ISIN US4710234653

CUSIP 471023465

Inception Date 1998-12-31

Domicile United States

Country USA

Fiscal Year End September

NAV Chart

Fund Metrics

Net Assets $5.36 Billion

Share Class Net Assets $1.62 Billion

Expense Ratio 0.77%

Expense Ratio Date 2025-01-28

Dividend Yield 0.00%

Morning Star Rating -

Morning Star Risk Rating -

Morning Star Category -

Performance

YTD Return 2.02%

1-Year Return 20.17%

3-Year Return 12.41%

5-Year Return 8.26%

NAV $82.80

Previous Close Price $83.21

Last Update 2025-12-31

Dividend Information

Dividend Yield 0.00%

Dividend (ttm) 0.17

Dividend Growth -58.12%

Payout Frequency Annual

Ex-Dividend Date n/a

Ratings

Morning Star Rating -

Morning Star Risk Rating -

Morning Star Category -

Beta (5Y) 1.23

About Janus Henderson Global Life Sciences Fund Class I

The fund pursues its investment objective by investing, under normal circumstances, at least 80% of its net assets (plus any borrowings for investment purposes) in securities of companies that the portfolio management believes have a life science orientation. In the fund's pursuit of companies with a life science orientation, the fund has a fundamental policy to normally invest at least 25% of its total assets in securities of companies that are categorized in the "life sciences" sector.

Detailed Metrics

Market Cap Distribution

AverageMarketCap 78438.50%

Giant 26.30%

Large 33.45%

Medium 16.22%

Micro 5.37%

Small 14.34%

Value & Growth Metrics

Book-Value Growth % 8.53%

Cash-Flow Growth % -7.52%

Dividend Yield % 1.13%

Historical Earnings % 1.70%

Long-Term Earnings % 9.77%

Asset Allocation

Type	Net %	Long %	Short %	Category Average	benchmark
Bond	0.00%	0.00%	0.00%	0.18%	0.00%
Cash	0.86%	0.86%	0.00%	1.44%	0.00%
Non US Stock	14.75%	14.75%	0.00%	8.38%	0.23%
Not Classified	0.74%	0.74%	0.00%	0.00%	0.00%
Other	0.47%	0.47%	0.00%	0.14%	0.00%
US Stock	83.18%	83.18%	0.00%	90.06%	99.77%

Top Holdings

Name	Weight	Owned	Change
Eli Lilly Co. COM NPV	8.31%	-	-
UnitedHealth Group Inc. COM USD0.01	4.21%	-	-
Novo Nordisk A/S SER'B'DKK0.1	3.65%	-	-
AstraZeneca PLC ORD USD0.25	4.22%	-	-
AbbVie Inc. COM USD0.01	3.58%	-	-
Merck Co., Inc COM USD0.50	3.28%	-	-
Amgen Inc. COM USD0.0001	2.87%	-	-
Sanofi EUR2	2.72%	-	-
Boston Scientific Corporation COM USD0.01	2.74%	-	-
Vertex Pharmaceuticals Incorporated COM USD0.01	2.35%	-	-
Johnson Johnson COM USD1.00	5.01%	-	-
Abbott Laboratories COM NPV	3.16%	-	-
Argenx SE SPON ADR EACH REP 1 ORD SHS	2.82%	-	-
Sanofi SA EUR2	2.69%	-	-
Novartis AG ADR-REP 1 CHF0.5 (REGD)	2.56%	-	-

See the full breakdown of JFNIX fund's asset allocation and top holdings .

Sector Weights

Category	Subcategory	Amount %	Category Avg	Stocks %	Benchmark
Bond Sector	Cash and Equivalents	0.00%	88.82%	53.71%	0.00%
Bond Sector	Corporate	0.00%	11.18%	46.29%	0.00%
Bond Sector	Derivative	0.00%	0.00%	0.00%	0.00%
Bond Sector	Government	0.00%	0.00%	0.00%	0.00%
Bond Sector	Municipal	0.00%	0.00%	0.00%	0.00%
Bond Sector	Securitized	0.00%	0.00%	0.00%	0.00%
Cyclical	Basic Materials	0.00%	0.00%	0.00%	0.00%
Cyclical	Consumer Cyclical	0.00%	0.00%	0.00%	0.00%
Cyclical	Financial Services	0.00%	0.02%	0.00%	0.00%
Cyclical	Real Estate	0.00%	0.14%	0.00%	0.00%
Defensive	Consumer Defensive	0.00%	0.00%	0.00%	0.00%
Defensive	Healthcare	100.00%	99.80%	0.00%	100.00%
Defensive	Utilities	0.00%	0.00%	0.00%	0.00%
Sensitive	Communication Services	0.00%	0.00%	0.00%	0.00%
Sensitive	Energy	0.00%	0.02%	0.00%	0.00%
Sensitive	Industrials	0.00%	0.01%	0.00%	0.00%
Sensitive	Technology	0.00%	0.00%	0.00%	0.00%

World Regions

Region	Subregion	Category Average	Stocks Percent	Benchmark
Americas	Latin America	-	-	-
Americas	North America	91.79%	85.20%	99.77%
Greater Asia	Asia Developed	0.09%	-	-
Greater Asia	Asia Emerging	0.10%	0.07%	-
Greater Asia	Australasia	0.07%	-	-
Greater Asia	Japan	0.40%	0.79%	-
Greater Europe	Africa/Middle East	0.26%	1.05%	-
Greater Europe	Europe Developed	5.28%	8.50%	0.10%
Greater Europe	Europe Emerging	-	-	-
Greater Europe	United Kingdom	2.01%	4.39%	0.13%

Dividend History

Date	Amount	Unadjusted Amount	Currency	Declaration Date	Record Date	Payment Date	Period
2024-12-06	$0.285	$0.285	USD	-	-	-	-
2023-12-07	$0.114	$0.114	USD	-	2023-12-06	2023-12-07	Annual
2022-12-20	$0.202	$0.202	USD	2022-12-20	2022-12-19	2022-12-20	Annual
2021-12-20	$0.909	$0.909	USD	2021-12-20	2021-12-17	2021-12-20	Annual
2020-12-17	$0.793	$0.793	USD	2020-12-17	2020-12-16	2020-12-17	Annual
2019-12-17	$0.534	$0.534	USD	2019-12-17	2019-12-16	2019-12-17	Other
2017-12-19	$0.244	$0.244	USD	2017-12-19	2017-12-18	2017-12-19	Other
2016-12-19	$0.166	$0.166	USD	2016-12-19	2016-12-16	2016-12-19	Other
2015-12-17	$0.211	$0.211	USD	2015-12-17	2015-12-16	2015-12-17	Other
2011-12-20	$0.044	$0.044	USD	-	2011-12-19	2011-12-20	Annual
2010-12-22	$0.153	$0.153	USD	-	2010-12-21	2010-12-22	Annual
2009-12-22	$0.021	$0.021	USD	-	2009-12-21	2009-12-22	Other

Janus Henderson Global Life Sciences Fund Class I NMFQS:JFNIX